About the Study
This study is looking at whether an investigational medication called depemokimab can help reduce future flare-ups in people with chronic obstructive pulmonary disease, or COPD in adults aged 40-75. The aim is to understand how well this medication works and how safe it is when added to a person’s usual COPD treatment.
Depemokimab has already been tested in previous clinical studies to understand its safety. This study builds on that knowledge by following people with COPD over a longer period of time.
The study is randomized, double-blind, and placebo-controlled to ensure high-quality, unbiased results. If you qualify and choose to participate, there is a 50% chance you will receive the study treatment and a 50% chance you will receive a placebo. A placebo is an inactive material that looks like depemokimab but does not contain any active ingredient. Everyone in the study will continue their regular COPD inhaler treatments throughout the study. Rescue medication will also be provided.
You will be on this study for approximately 1-3 years, depending on when you enter the study, which will include a screening period, a run-in period, a treatment period, and a follow-up period. The study will require up to 18 in-clinic visits and 23 remote visits. If you qualify and choose to participate, you may be compensated up to $1,800 for your study-related time and travel. Your participation is entirely voluntary, and you can leave the study at any time.